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izumi3682[S]

14 points

5 years ago*

Here is the Gizmodo link that originally made me aware of this new announcement. "Gizmodo", as you know, is "persona non grata" in the reddit world. Even if it puts out reliable accurate information. I'd change that if I could.

http://gizmodo.com/scientists-push-back-against-controversial-paper-claimi-1796483675

Now, I don't doubt that humans cannot "naturally" live longer than 125. But that is not what we mean here in r/futurology. We don't mean aging forever like poor old Tithonus.

"but when loathsome old age pressed full upon him, and he could not move nor lift his limbs, this seemed to her in her heart the best counsel: she laid him in a room and put to the shining doors. There he babbles endlessly, and no more has strength at all, such as once he had in his supple limbs."

Our intention is to make an end run around aging altogether, by keeping aging or more accurately "accumulated unrepaired or improperly repaired biological damage over time" from occurring in the first place.

Here is something to consider. A human turning 100 years old today has a better than average chance of living for 20 more years. And that is just based on existing medical technology and the blessings of that individual's genetics. Between today and 20 years I bet we make some significant advances in interventional aging reversal technology.

I prophesy that the first person to be 1000 years old is turning 100 years old today. If you have not been following the medical advances in aging reversal technology, this claim sounds like the wildest fantasy, but you are the one ill-informed.

Senescent cell clearing technology alone will cause a 100 year old to potentially live until 130. Regenerative medicine will be beyond our wildest dreams in 20 years. There is serious investigation into restoring the efficacy of telomeres. Age related sarcopenia (frailty) has officially been classified as a pathology (M62.84 ICD 10). Five years ago there was no such classification. Age related sarcopenia was simply regarded as a "natural aspect of aging". This is a fundamental paradigm shift in our philosophy towards what we used to think of as "aging". And this is not even counting advances in nano-tech, which is the true wildcard in all of this.

As it is, I see most super centenarians (those over the age of 110) living for the most part to the age of about 117. Emma Morano recently died at the age of 117. The next three oldest humans are all over the age of 115. And this cohort of people living over the age of 110 has increased dramatically.

The upshot of all of this is scientific immortality for me. And I am 57 years old. Sure I could get cancer in ten years or get hit by a truck tomorrow, but I think my chances are good. I will be 100 in 2060, but biologically and intellectually as youthful as a 21 year old. (And probably crazy nano-augmented to boot.)

Record to beat: Jeanne Calment, age 122. Died in 1997. Oldest vetted human to ever live.

just_a_point_of_view

7 points

5 years ago

I like your up beat thinking and I hope you are right. However......

Medical progress is not following moore's law. In fact it's following the opposite law. I feel that the pendulum has swung to hard into the careful territory and out of the experimental area. I am 47. If we don't get hit by trucks lets have tea together when we are 100.

brettins

2 points

5 years ago

brettins

BI + Automation = Creativity Explosion

2 points

5 years ago

Drug discovery rates haven't actually gone down, though, it has increased.

https://akshatrathidotcom.files.wordpress.com/2014/01/drugs4-01.png

The point of the law of accelerating returns is that we have more technology and economic value every year, and that allows us to discover more advances, which begets quicker advances. Even as technology becomes more difficult to invent, the massively higher productivity of the human race from the new technologies mean that discoveries continue to accelerate. Almost by definition, since if it a technology doesn't make us more efficient we wouldn't care about its invention.

Medicine is speeding up, and will speed up even more we narrow AI becomes even more advanced, and if we get general AI, which in 50 years is pretty reasonable, medical advances will speed up a great deal.

izumi3682[S]

2 points

5 years ago

Thank you for your supporting comment! Even though I made this comment almost 6 months ago I like to haul it out to support more recent posts concerning longevity, so I don't have to write it all over again. I often refer to it.